Vol. 30 No. 1 (2026): XXX Meeting of the Spanish Environmental Mutagenesis and Genomics Society

Vol. 30 No. 1 (2026)

Published May 31, 2026
XXX Meeting of the Spanish Environmental Mutagenesis and Genomics Society

This issue of the Spanish Journal of Environmental Mutagenesis and Genomics includes the abstracts of the communications presented during the XXX Meeting of the Spanish Environmental Mutagenesis and Genomics Society | SEMA (June 10th-12th, 2026).

Full Issue
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Keynote Lectures

F. Esteves, J. Madureira, S. Bonassi, S. Costa, J. P. Teixeira
9
Inside the fire: advancing human biomonitoring in firefighters
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T. Roldán Arjona
10
Base excision: evolving complexities of a crucial pathway for epigenetic control and DNA repair
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M. Durán-Prado
11
When wonder materials meet DNA; graphene’s toxic and genotoxic footprint
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D. Guallar
12
Time Written in RNA: The Epitranscriptomic Code of Ageing
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A. J. Arana, L. Sánchez
13
Zebrafish as a Versatile Vertebrate Model for Cancer, Rare Disease, and Toxicology Research
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V. Bolón-Canedo, M. Martínez-Matamoros, L. Morán-Fernández, N. Fernández-Bertólez, B. Laffon, V. Valdiglesias
14
AI for toxicology: in silico tools to reduce experimental testing
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Human biomonitoring in clinical, occupational and environmental settings

M. Gerić
16
The assessment of health-related biomarkers among different dietary patterns
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A. Hemadeh, C. Lema-Arranz, S. Bonassi, L. Buscarini, F. Infarinato, P. Romano, A. Finti, F. Marinozzi, F. Bini, N. Fernández-Bertólez, L. Lorenzo-López, V. Valdiglesias, B. Laffon
17
Lifestyle, environment, and major determinants of frailty: UK Biobank study
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C. Lema-Arranz, A. Hemadeh, N. Cibeira, R. López-López, J. L. Rodríguez-Villamil, J. C. Millán-Calenti, A. López-Cortón, N. Fernández-Bertólez, V. Valdiglesias, L. Lorenzo-López, B. Laffon
18
Endocrine biomarkers for physical and cognitive frailty in older adults
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J. A. Lema-Atán, E. Lendoiro, A. Cruz, B. Bernárdez, M. Cobo-Golpe, N. Mayo, M. Blanco-Ces, M. Tourís, A. López-Rabuñal, I. Zarra, M. López-Rivadulla, A. de-Castro-Ríos
19
Occupational exposure to cytostatic drugs: combined environmental and biological monitoring in a Spanish hospital
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DNA repair and genome instability

R. Santiago-Domínguez, A. Muñoz-Fernández, S. Conde-Maestre, T. Morales-Ruiz, R. R. Ariza, T. Roldán-Arjona, M. I. Martínez-Macías
21
Role of an AP Lyase pathway in the repair of AP sites generated by DNA methylating agents
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Y. Lorenzo, B. O. Nicolaissen, G. Nguyen, K. Beraki, M. C. Moe, G. Petrovski, D. Krohn-Hansen, B. Nicolaissen
22
DNA oxidation damage and expression of the DNA repair enzyme OGG1 in organ-cultured human conjunctival epithelial cells
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M. Saavedra-Rodríguez, A. Touzani, L. Ramos-Pan, A. Insua, M. A. Maestro, N. Fernández-Bertólez, B. Laffon, V. Valdiglesias
23
Assessment of cytotoxicity and genotoxicity in human glial cells exposed to platinum nanoparticles
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G. Gajski, K. Matković, M. Gerić, A. Cvitković, M. Sanković, V. Kašuba, M. Milić, L. Kazensky, A. Jurič, I. Brčić Karačonji, I. Jakovljević, S. Davila, G. Pehnec, A. M. Domijan, A. Šumanovac, P. Wild, I. Guseva-Canu, N. B. Hopf
24
Living with higher air pollution: Does it affect genomic stability?
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Environmental and health risk assessment of emerging pollutants (I)

A. T. Reis, F. Rosário, C. Costa, C. Vilaça, C. Lopes, A. C. Estrada, V. Valdiglesias, J. P. Teixeira
26-27
Genotoxic responses to nanomaterials and metal(loid)s co-exposure: insights from complementary DNA damage biomarkers
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R. S. Vilela, C. Ventura, B. Guerreiro, H. Louro, M. J. Silva
28
Comparative genotoxicity of Alternaria mycotoxins in HepG2 cells
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H. R. Van Goethem, A. Vergara, I. H. Valido, S. Pastor
29
Assessment of genotoxic effects induced by real-life micro- and nanoplastics derived from orthodontic thermoplastics
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K. Barrios-Garay, A. Rocabert, O. Camps-Font, E. Valmaseda-Castellón, S. Pastor-Benito
30
Changes in the oral microbiota after six months of clear aligner orthodontic treatment: Assessment of micro- and nanoplastic exposure using MinION sequencing
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H. Pulli, T. Venus, M. Venäläinen, D. Abass, J. Domenech, D. Angosto, M. Morataya-Reyes, C. Moreno, K. Siivola, L. Martínez-Alarcón, K. Portillo, P. Millán-Billi, E. Cervera, I. Estrela-Lopis, P. Pelegrín, A. Hernández, S. Pastor, J. Catalán
31
Genotoxic effects in workers of the plastic recycling industry exposed to micro- and nanoplastics
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Epigenomics and epitranscriptomics, and emerging pollutants (II)

C. Ayala-Roldán, L. G. Bermúdez Liscano, J. Romero Simmonds, R. R. Ariza, T. Roldán-Arjona, T. Morales-Ruiz, A. P. Rojas Moreno
33
H3K27 acetylation as a key regulator of onco-lncRNA expression in lung cancer
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I. Barguilla, L. Billon, K. Geistlich, J. Gutiérrez-García, R. Egea, L. Rubio, S. Jeanpierre, A. Hernández, B. Guyot, V. Maguer-Satta
34
Chronic exposure to nanoplastics alters stem cell type-specific mechanisms, promoting cancer development
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A. García-Rodríguez, J. Martín-Pérez, J. Gutiérrez-García, R. Egea, R. Marcos, A. Hernández
35
Genotoxic and functional endothelial responses to nanoplastics: the role of physicochemical properties
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J. Arribas Arranz, I. Barguilla, C. Pommerenke, R. Egea, M. Morataya-Reyes, A. Villacorta, P. Pelegrín, J. F. Ferrer, J. Catalán, R. Marcos, A. Hernández
36-37
An innovative biomarker-based blood assay for monitoring micro- and nanoplastic exposure in occupational and environmental settings
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R. Egea, A. Rocabert, M. Gámez, M. Alaraby, A. García-Rodríguez, R. Marcos, A. Hernández
38
Multi-omic analysis of the biological impacts of exposure to PTFE micro- and nanoplastics in Drosophila melanogaster
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Animal models in toxicity testing and human disease research

L. Ramos-Pan, M. Novak, A. Touzani, M. Saavedra-Rodríguez, M. Paz, J. Mosquera, A. Criado, M. L. Díaz-Prado, N. Fernández-Bertólez, B. Laffon, B. Zegura, V. Valdiglesias
40
In vivo evaluation of three differently charged gold nanoparticles using the zebrafish embryo model
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A. Touzani, M. Saavedra-Rodríguez, L. Ramos-Pan, A. Insua, J. Moreda-Piñeiro, N. Fernández-Bertólez, B. Laffon, V. Valdiglesias
41
Toxicity assessment of platinum nanoparticles in Drosophila melanogaster: acute and chronic exposure effects
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D. López-Aragón, L. Ramos-Pan, L. Martínez, J. Moreda-Piñeiro, B. Laffon, V. Valdiglesias
42
Morphological and behavioural alterations in Drosophila melanogaster offspring and adults after developmental exposure to gold nanoparticles
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M. Alaraby, D. Abass, R. Egea, A. Velázquez, A. Hernández, R. Marcos
43
Hazard impacts of polytetrafluoroethylene micro-nanoplastics: in vivo study
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J. L. R. Rama, M. Cabaleiro, N. Bocija-Villaverde, S. Cabaleiro, N. Mallo
44
Natural flavonoids induce dose-dependent cytotoxicity in marine ciliated protozoa parasites through putative mitochondrial mechanisms
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New Approach Methodologies in toxicity/safety assessment

M. Benito-Fuertes, A. Rodríguez-Garraus, A. Azqueta
46
Evaluation of New Approach Methodologies (NAMs) for the detection of compounds classified as non-genotoxic carcinogens (NGTxCs)
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C. Ramos, C. Ventura, A. Tavares, H. Louro, M. J. Silva
47
Model matters: Comparative toxicity of BPA and BPS-MAE in 2D and 3D HepG2 models
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S. Maisanaba, M. Cano-Caballero, H. Flores-Mayal, C. Álvarez-Herrera, R. Rojas, Ó. Herrero, R. Planelló, A. P. Zaderenko, R. García-Repetto, M. Llana-Ruiz-Cabello, G. Repetto
48
Use of the nematode Caenorhabditis elegans as a biomodel to investigate the toxic effects of the plasticizer bisphenol A and their chemical analogues
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J. Gutiérrez-García, S. Trischitta, G. M. Ferraz, L. Pareras, C. Anguita-Soler, R. Marcos, A. Hernández, L. Rubio
49
Micro- and nanoplastic interference in THP-1 immune response in an inflammatory context
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J. Gutiérrez-García, L. Pareras, G. M. Ferraz, S. Trischitta, R. Marcos, A. Hernández, L. Rubio
50
Unraveling the effects of real-life micro- and nanoplastics on the lung barrier using an ALI co-culture model
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