Vol. 29 No. 1 (2025): XXIX Meeting of the Spanish Environmental Mutagenesis and Genomics Society
XXIX Meeting of the Spanish Environmental Mutagenesis and Genomics Society

This issue of the Spanish Journal of Environmental Mutagenesis and Genomics includes the abstracts of the communications presented during the XXIX Meeting of the Spanish Environmental Mutagenesis and Genomics Society | SEMA (May 21st-23rd, 2025).

Full Issue
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Keynote Lectures

A. Ruiz-Herrera
9
Genome plasticity in three dimensions: exploring the dynamics of chromatin folding across time-scales and cell types
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B. Laffon, C. Lema-Arranz, A. Hemadeh, N. Cibeira, R. López-López, J. L. Rodríguez-Villamil, A. Maseda, J. C. Millán-Calenti, J. Méndez, A. López-Cortón, E. Pásaro, N. Fernández-Bertólez, V. Valdiglesias, L. Lorenzo-López
10
Physiopathology of frailty in older adults: development of biomarkers for its early identification
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M. Bustamante, H. Vespalcová, L. Balagué-Dobón, B. Knox, S. Aguilar, M. Cosin, A. K. Sakhi, C. Thomsen, P. Dadvand, M. Vrijheid
11
Chemical exposure in early-life: epigenetic mechanisms and genetic susceptibility
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A. Laromaine
12
Exploiting C. elegans to assess Nanotechnology and nanomedicine
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M. Garcia, I. Brandts, M. Teles, F. Chauvigné, J. Cerdà, P. De Oro-Carretero, J. Sanz-Landaluce, G. Pujol, A. Ruiz-Herrera, N. Roher
13
Under the Surface: how the cells and tissues from aquatic organisms respond to Polystyrene Nanoplastic Exposure
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Genomics, epigenetics and evolution

H. Van Goethem, A. Rocabert, J. Cabrera, M. Alaraby, A. García-Rodríguez, J. Martín-Pérez, J. Martínez-Urtaza, C. Bussy, A. Kuttykattil, R. Marcos, A. Hernández
15
Studying the effects of nanoplastics in the gastrointestinal microbiota of Mus musculus
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Z. Keer, A. Rocabert, M. Alaraby, R. Egea, R. Marcos, A. García-Rodríguez, A. Hernández
16
Studying the effects of Teflon® micro- and nanoparticles on the gastrointestinal microbiota
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R. Egea, J. Arribas, C. Pommerenke, R. Marcos, A. Hernández
17
Single-cell transcriptomics analysis of ex vivo nanoplastic exposed human whole blood as a model to understand their impact on human health
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DNA damage and repair, genome instability and human disease

I. Gaivão, A. R. Guedes
19
Base and nucleotide excision DNA repair mechanisms activity in equines: Insights into disease resistance, longevity, and lifestyle
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Y. Lorenzo, B. O. Nicolaissen, G. Nguyen, K. Beraki, M. C. Moe, G. Petrovski, D. Krohn-Hansen, B. Nicolaissen
20
Expression of DNA repair enzyme APE1 in non-cultured and organ cultured corneal- and limbal epithelium
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E. Teixidó, A. S. Maddaleno, L. Pous, L. Guardia-Escoté, E. Reig, M. Aznar, M. P. Vinardell, M. Mitjans
21
Evaluating the suitability of the alkaline comet assay in HaCaT cells for predicting photogenotoxicity
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A. Rodriguez-Garraus, E. Saenz-Martinez, M. Collia, A. López de Cerain, A. Gil, A. Azqueta
22
Can potassium bromate be used as a positive control in the in vivo Fpg-modified comet assay?
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C. Camps-Fajol, J. Surrallés
23
DNA damage response inhibitors targeting synthetic lethal interactions for cancer treatment
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Health hazard assessment of emerging pollutants

S. Gascón-Corella, I. P. Oswald, A. Vettorazzi
25
Genotoxic characterization of emerging mycotoxins in vitro
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N. Fernández-Bertólez, L. Ramos-Pan, A. Touzani, A. T. Reis, J. P. Teixeira, J. Mendez, B. Laffon, V. Valdiglesias
26-27
Biocompatibility and antioxidant potential of nanoceria in human nervous cells
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N. Miranda, V. V. Tkach, A. Martins-Bessa, I. Gaivão
28
Biological impact of the sweetener sucralose – an in vivo study in Drosophila melanogaster
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M. Pérez, C. Furió, A. Fernandez, J. F. Ferrer
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In vitro bioassays as a tool to evaluate risk assessment of micro and nanoplastics
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D. Abass, M. Alaraby, A. García-Rodríguez, H. M. Morataya Reyes, G. Banaei, J. Martín Pérez, A. Hernández, R. Marcos
30
Intestinal impact of PTFE-derived micro- and nanoplastics
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J. Martín-Pérez, A. Villacorta, J. Gutierrez, R. Egea, M. Morataya-Reyes, M. Cassú-Casadevall, R. Marcos, A. Hernández, A. García-Rodriguez
31
Size-dependent effects of polystyrene nanoplastics on human primary endothelial cell function
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Human biomonitoring I

C. Lema-Arranz, A. Hemadeh, N. Cibeira, R. López-López, J. L. Rodríguez-Villamil, A. Maseda, J. C. Millán-Calenti, J. M´éndez, A. López-Cortón, E. Pásaro, N. Fernández-Bertólez, V. Valdiglesias, L. Lorenzo-López, B. Laffon
33
Inflammation and frailty: association of immunological biomarkers with physical and cognitive impairment in older adults
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S. Sierra, P. Ayala, A. Cañas, A. Rojas, A. Vergara
34
Analysis of DNA damage by e-cigarettes exposure in a youth population
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A. Rocabert, J. Catalán, J. Domenech, H. Pulli, S. Pastor, A. García-Rodríguez, R. Egea, R. Marcos, A. Hernández
35
Integrating microbiota profiling in biomonitoring of occupational exposure to micro- and nanoplastics
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New approach methodologies in toxicity and risk assessment

M. Benito-Fuertes, A. Rodriguez-Garraus, A. Azqueta
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In vitro evaluation of genetic instability and cellular transformation capacity as potential biomarkers of non-genotoxic carcinogens
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J. Gutiérrez-Gracía, R. Egea, I. Barguilla, P. Nymark, A. García-Rodríguez, B. Guyot, V. Maguer-Satta, R. Marcos, L. Rubio, A. Hernández
38
Long-term exposure to secondary polyethylene terephthalate nanoplastics induces carcinogenesis in vitro
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I. Barguilla, J. Gutierrez-García, L. Billon, R. Egea, L. Rubio, A. Hernández, B. Guyot, V. Maguer-Satta
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Stem cell models to study long-term effects of PS and PET nanoplastics: a focus on cell transformation
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C. Anguita-Solé, J. Gutiérrez-García, L. Rubio, A. Hernández
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Establishment of a human pulmonary in vitro co-culture model for nanoplastic toxicological assessment: Calu-3 and THP-1 macrophages
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Ecotoxicity and reproductive toxicity

L. Rubio, I. Due, E. Anton, L. Tusell, J. Catalán, S. Foss, E. Ibáñez
43-44
Quality evaluation and review of in vivo mammalian reproductive and developmental toxicity studies on micro- and nanoplastics
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A. Clarà, T. Gentz, Y. El Ouahi Hajji, A. Pumarola, A. Blanquer, L. Tusell, Z. Sarrate, M. Martín, J. Blanco, E. Anton, E. Ibáñez
45
The impact of nanoplastics on mammalian reproductive function: an in vitro study with gametes, embryos and placental cells
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M. Alaraby, D. Abass, J. Gutiérrez, A. Hernández, R. Marcos
46
Reproductive toxicity of nanomaterials. Silver nanoparticles and Drosophila as models
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Educational resources

Ó. Herrero, A. Azqueta
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RALDE: Re-thinking Active Learning for Distance Education
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A. García-Rodriguez, R. Egea, L. Rubio-Lorente, I. Barguilla, J. Gutiérrez-García, J. Martín-Pérez, G. Banaei, H. M. Morataya-Reyes, A. Rocabert, R. Marcos, A. Hernández
53-54
Engaging the youngest minds; communicating environmental mutagenesis through microplastic pollution education at the European Researchers’ Night
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E. de la Peña, Ó. Herrero
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Activities in Iberoamerica of the Iberoamerican Network of Toxicology and Chemical Safety
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I. Barguilla, A. García-Rodriguez, R. Egea, L. Rubio-Lorente, J. Gutiérrez-García, J. Martín-Pérez, G. Banaei, M. H. Morataya-Reyes, A. Rocabert, R. Marcos, A. Hernández
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The PELAGOS expedition: science beyond the lab
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L. Rubio-Lorente, A. García-Rodriguez, R. Egea, I. Barguilla, J. Gutiérrez-García, J. Martín-Pérez, G. Banaei, H. M. Morataya-Reyes, A. Rocabert, R. Marcos, A. Hernández
57-58
PlasticHealers: an interactive journey through the health effects of micro- and nanoplastics
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Ó. Herrero, A. Azqueta
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ToxLearn4EU: Toxicology Innovative Learning for Europe
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R. Egea, A. García-Rodriguez, L. Rubio-Lorente, I. Barguilla, J. Gutiérrez-García, J. Martín-Pérez, H. M. Morataya-Reyes, G. Banaei, A. Rocabert, R. Marcos, A. Hernández
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Mutagens and Experiment al lab card games: innovative and alternative resources for introducing gamification within education in bioscience
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